Warfarin is a type of medicine known as an anticoagulant, or blood thinner.

It makes your blood flow through your veins more easily. This means your blood will be less likely to make a dangerous blood clot.

Warfarin is used to treat people who have had a previous blood clot, such as:

• a blood clot in the leg (deep vein thrombosis, or DVT)
• a blood clot in the lungs (pulmonary embolism)

It's also used to prevent blood clots if you're at high risk of having them in the future.

This includes people with: * have an abnormal heartbeat (atrial fibrillation) * a replacement or mechanical heart valve * a blood clotting disorder, such as thrombophilia * a higher chance of having a blood clot after an operation

Warfarin is only available on prescription. It comes as tablets and as a liquid that you swallow.

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One group of 15 patients had overactivity of tibialis anterior in the swing phase, and underwent the split transfer. Mobile phases containing aqueous solution of formic acid, acetic acid, acetonitrile, and methanol were tested. With simple constraints, redesigned genes have provable maximal number of hidden stops. The delay may reflect complex bio-reactions such as those of metabolism in a human body. Furthermore, we show robust expression of PUR proteins in failing hearts where alpha-MHC mRNA levels are suppressed.

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Because our previous studies had correlated activation of the metabolic turnover of the phosphatidylcholine (PC) fraction of membrane phospholipids with enhanced Ig secretion, we examined the sensitivity of PC metabolism to cAMP in control and PMA-stimulated cells. Sex hormones, HDL cholesterol and other lipoproteins in older males The effect of 1,25-dihydroxyvitamin D3 on the growth and differentiation of cultured human outer root sheath cells from normal subjects and patients with vitamin D-dependent rickets type II with alopecia.

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Synthesis of cytokeratin 13, a component characteristic of internal stratified epithelia, is not induced in human epidermal tumors. Pharmacological characterization of the bradykinin B2 receptor: inter-species variability and dissociation between binding and functional responses.

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actinomycetemcomitans in children and adolescents may be a useful marker for aggressive periodontitis. VTE occurring in hospitalized patients carries a significantly higher risk for death of PE than in outpatients, underscoring the importance of VTE prevention strategies in the hospital setting. Resnick and Novick led a golden age of urology for several decades until their recent untimely passings. The traumas used were hepatic rupture, flail chest, haemothorax, and femoral fracture. On the first night, the PTSD subjects had a higher density of rapid eye movements in the first REMS period.

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In the first experiment, a between-subjects experimental design was used to compare four groups of eight university males for their erectile responses to vignettes rated as low, medium, and high along a victim blame continuum. No obvious occupational hazard explains the increased risk specific to men across a wide range of textile occupations.

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Hepatobiliary scintigraphy is noninvasive and useful in the detection of a biliary enteric fistula and lesions about related organs. Cerebral ischemia: changes in brain choline, acetylcholine, and other monoamines as related to energy metabolism.

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The Al(2)O(3) nanomask prevented the Au and AgNPs from thermal coalescence even at 500 degrees C, and consequently, it improved thermal stabilities of nanoparticle ensembles. To evaluate the nutritional status of mentally retarded children in the region of Galicia, northwest Spain, on the basis of serum biochemistry variables.

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Ibuprofen was chosen as a representative of currently used nonsteroidal antiinflammatory drugs. Translocation of Pseudomonas aeruginosa from the intestinal tract is mediated by the binding of ExoS to an Na,K-ATPase regulator, FXYD3.

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Assigning stereochemistry to single diastereoisomers by GIAO NMR calculation: the DP4 probability. Designing for topical delivery: prodrugs can make the difference. When both wortmannin and PD98059 are infused during E(2) priming, lordosis behavior is completely abolished. A comparison with skinfold thickness measured in Jena schoolchildren three decades ago showed a significant increase in subcutaneous fat.

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Gene pthA is required for virulence of Xanthomonas citri on citrus plants and has pleiotropic pathogenicity and avirulence functions when transferred to many different xanthomonads. HERF1, a novel hematopoiesis-specific RING finger protein, is required for terminal differentiation of erythroid cells. Characterization of a legumain/vacuolar processing enzyme and YVADase activity in Papaver pollen. In 2 patients examination of 200 obstructive, mixed and central apneic events showed no significant differences in recordings of their incidence, duration of classification between polysomnographic and either pharyngeal or esophageal pressure techniques. Antigen-specific helper function of cell-free T cell products bearing TCR V beta 8 determinants.

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The design of the study and the perioperative management of the patients are described in detail and the results analyzed according to clinical course, blood tests and abdominal ultrasound. On April 16, 2003, World Health Organization (WHO) formally declared that SARS-CoV was an etiological agent of SARS. Population-based cancer incidence in Sikkim, India: report on ethnic variation. Single and double regimes had some effect, but were not nearly so successful as triple treatment.

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A consecutive series of patients under the care of a single surgeon (D.B.) underwent laparoscopic restoration of intestinal continuity (LapRICon). We evaluate early results of bovine jugular vein conduits in the pulmonary outflow.

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After 1 week, high and low responders to the acupuncture treatment were selected according to their cigarette consumption and the desire to smoke. I report the case of a woman who, in three successive pregnancies, gave birth to premature infants with septicaemia due to non-capsulate Haemophilus influenzae. With the increasing use of MRI as a diagnostic tool, it is useful to establish a classification of prosthetic biomaterials compatible with MRI. Orally administered cephalosporins are beta-lactamic broad-spectrum antimicrobial agents that are often used empirically to treat community bacterial infections and also to treat culture-proven infections due to selected gram-positive and gram-negative microorganisms. It is assumed that the bioactive components produced by lactic acid fermentation induced the up-regulation of CYP7a1.

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Data were only included from questionnaires returned by people known to carry disease causing mutations. The purified AAA domain of Yme1 binds unfolded polypeptides and suppresses their aggregation.

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Monitoring EMS protocol deviations: a useful quality assurance tool. 3-DG and 3-DGal were quantified besides 3-deoxypentosone, methylglyoxal, and glyoxal after derivatization with o-phenylenediamine in lactose-hydrolyzed UHT milk, ranging from 2.5 to 18 mg/L and from 2.0 to 11 mg/L, respectively.

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An ECG signal is cut and aligned to form a 2-D data array, and then 2-D wavelet transform and the modified SPIHT can be applied. An update on the diagnosis and management of dementing conditions. However, little is known about the molecular aspects of the regulation and activation of large numbers of MAP3Ks that are crucial in relaying upstream receptor-mediated signals through the MAPK cascades to induce various physiological responses. The synthesis of a Tentagel-supported peptide incorporating the reactive triad of serine, histidine and aspartic acid, found within serine protease enzymes, is described.

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Effort thrombosis is a rare vascular condition of the upper extremity that may be seen in workers with repetitive, forceful, or overhead arm activities. The purpose of this study was to characterize the role of the capsule in the interval between the supraspinatus and subscapularis tendons with respect to glenohumeral motion, translation, and stability. Therapy for prostatic infections requires an agent that penetrates prostatic tissue and secretions, such as trimethoprim-sulfamethoxazole or, preferably, a fluoroquinolone.

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Leaf pigments of Lycium europaeum: seasonal effect on zeaxanthin and lutein formation. Results suggest that performance differences on semantic tasks with limited retrieval demands in schizophrenia relate to difficulties utilizing higher-order categorization strategies. Inhibitory monoclonal antibodies were used to identify specific blockade of cell surface integrins GPIIb/IIIa (alphaIIbbeta3) and GPIa/IIa (alpha2beta1), the platelet receptors for fibrinogen and collagen, respectively. This approach demanded unique evaluation approaches for determining overall community aggregate effects, that is, distal outcomes, as well as changes in key mediating variables, that is, process effects. Synovial biopsy specimens from 23 SpA patients before and after infliximab or etanercept treatment, from 15 RA patients, and from 18 osteoarthritis (OA) patients were analyzed by immunohistochemistry.

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We previously reported that positron emission tomography (PET) with 18-F-fluorodeoxyglucose (FDG) might be a useful tool for evaluating the stage of esophageal squamous cell carcinoma (SCC), and that FDG-PET shows greater accuracy in the diagnosis of lymph node metastasis than computed tomography. SDF-1 versus RANKL effects on chemotaxis, transcollagen migration, MMP-9 expression and activity, OC development, and bone resorption were evaluated in RAW cells or RAW-OCs. Cancer Internet search activity on a major search engine, United States 2001-2003. Cloning of their respective precursors was achieved from lyophilized venom cDNA libraries for the first time.

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These viruses mostly occurred in the context of co-infections with other hepatitis viruses. We investigated the dark cell area of human vestibular organs in order to clarify the ultrastructural evidence for cell interaction between epithelial dark cells and melanocytes. An extensive panel of immunohistochemical stains revealed strong diffuse staining with keratin and epithelial membrane antigen in all three cases as well as patchy membrane staining with an antibody to CD34.

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A case of multiple epitheliopathy associated with sub-retinal neovascularization A paucity of data exists relating to clinical and echocardiographic features of ILVNC in Africans. We have found a surfactant-promoted novel reductive synthesis of metallic Cu nanoclusters on metal oxides under hydrothermal synthesis conditions, which are active for the selective dehydrogenation of methanol.

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In contrast, with methods based on the use of strong fixatives, such as methanol or acetone, the small molecules diffuse into the cytosol and in the case of oligonucleotides into the nucleus. Eosinophilia, lead poisoning and Toxacaris canis infection in children. The adhesion plaques in vitro are the equivalent of the in vivo intercalated discs, both in terms of their molecular composition and with respect to their functioning as initiating sites for the assembly of new sarcomeres. The high value of DeltadenCp for succinylated lysozyme is explained in terms of an extended degree of unfolding of the secondary structure and exposure of the apolar parts of the succinyl groups. The authors present their experience in treating 142 patients with severe viral respiratory infection caused by influenza A (H1N1), describe its clinical picture, and identify major syndromes observed in the treatment of these patients at an intensive care unit.

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Detection of human myeloid progenitor cells in a murine background. Cortical functions related to hand-eye coordination may be affected by transient changes in postoperative stereoacuity. Embryonic gonadotropin-releasing hormone signaling is necessary for maturation of the male reproductive axis.

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A detection limit equal to 5 ppb for Pd has been finally achieved. Phase-transition-like properties of double-beam optical tweezers.

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Experimental results are presented on the characterization of thin (3-12-nm) a-Si:H films on top of thermally oxidized crystalline silicon. The rise in cTnI may be explained by a degree of myocardial involvement, albeit physiological. The density of substance P receptor binding sites observed in this glial scar is among the highest observed in the rabbit forebrain.

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Distal motor latencies of the deep branch of the ulnar nerve to the first dorsal interosseous were significantly prolonged after the long-distance cycling event. Importance of questionnaire context for a physical activity question. However, it is located on chromosome 3, in contrast to other gamma genes which occur in tandem on the human chromosome 2. We found that the nuclear TC45 phosphatase is most likely responsible for the phospho-S727-dependent pY705 dephosphorylation because TC45 knockdown caused prolonged pY705 with sustained socs3 mRNA expression in STAT3WT but not in STAT3S727A, and overexpressed TC45 caused rapid dephosphorylation of pY705 in STAT3WT but not in STAT3S727A.

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The loss of dexamethasone protection was associated with a diminished accumulation in XIAP and c-IAP proteins. Administration of free terrilytin to the infected mice increased the immune response development induced by SRBC while the use of immobilized terrilytin normalized it. Myeloperoxidase activity in the lung tissue was measured by a new chemiluminescence method to quantitate pulmonary neutrophil sequestration. However, infarct size did not predict the occurrence of long-term complications. Retrograde salvage approach to treat tibial artery perforation during attempted revascularization of a chronically occluded artery.

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Hypersensitivity reactions to chemotherapy agents in patients receiving chemoimmunotherapy with high-dose interleukin 2. Transplantation: Expression levels of iron homeostasis genes predict liver graft tolerance. We report a novel case of schwannoma arising from the vagus nerve and review the diagnostic strategies.

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The downregulation of SEMA5A in tumor tissue, both at the transcriptional and translational levels, was associated with poor survival among nonsmoking women with NSCLC. We show here that PPARbeta protects keratinocytes from growth factor deprivation, anoikis and TNF-alpha-induced apoptosis, by modulating both early and late apoptotic events via the Akt1 signaling pathway and DNA fragmentation, respectively. However, the primate face constitutes a unique structure where the diverse and potentially competing functions of communication, ecology and physiology intersect, and the major determinants of facial diversity remain poorly understood. The addition of sera collected 1 hr after anesthetic induction significantly reduced the numbers of two-cell mouse embryos that developed to blastocyst in the ISO/N2O group as compared to that of preanesthesia sera. To assess inter/intraobserver variability in the interpretation of a series of digitised images of columnar cell lesions (CCLs) of the breast.

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