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Physicochemical characterization and pharmacological evaluation of Ezetimibe-PVP K30 solid dispersions in hyperlipidemic rats. Patients with known CAD, who were being treated with simvastatin 20 mg and had low-density lipoprotein cholesterol (LDL-C) concentrations of 2.6 to 4.1 mmol/l, were randomized to receive daily coadministration of Ezetimibe 10 mg or placebo.

Other names for this medication:
Ezetimibe, Zetia, Ezedoc, Ezetimiba, Ezetrol, Zient,

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Ezetimibe is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. It may be used alone or in combination with an HMG-CoA reductase inhibitor (statin). Ezetimibe is in a class of medications called cholesterol-lowering medications. It works by preventing the absorption of cholesterol in the intestine.

Buildup of cholesterol and fats along the walls of the blood vessels (a process known as atherosclerosis) decreases blood flow, which decreases the oxygen supply to the heart, brain, and other parts of the body. Lowering blood levels of cholesterol and fats may help reduce this buildup and may decrease your chances of developing heart conditions such as angina (chest pain), strokes, and heart attacks. Results of a clinical study that compared people who took ezetimibe and simvastatin with people who took simvastatin alone found that although the group of people taking ezetimibe and simvastatin had lower amounts of cholesterol in the blood, there was no difference between the two groups in the amount of cholesterol and fat buildup on the insides of the blood vessels in the neck. It is not currently understood why the additional lowering of cholesterol levels in the blood did not lead to a greater decrease in cholesterol and fat buildup along the walls of the blood vessels in people taking ezetimibe and simvastatin. Further studies are underway to compare treatment with ezetimibe and simvastatin to treatment with simvastatin alone to see if there is a difference in the risk of developing heart disease. Talk to your doctor if you have questions about the risks and benefits of treating increased amounts of cholesterol in your blood with ezetimibe and other medications.

In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your blood cholesterol levels. You should eat a diet that is low in saturated fat and cholesterol (see SPECIAL DIETARY); exercise 30 minutes on most, if not all, days; and lose weight if you are overweight.

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To determine the risk of all cause mortality, cause specific mortality, and incident cancer in meatworkers. Role of endosonography in the evaluation of gastric malignancies. The post two-step electrocardiogram and hemodynamic determinants of myocardial oxygen consumption.

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Scopolamine impairs acquisition and facilitates consolidation of fear conditioning: differential effects for tone vs context conditioning. Direct analysis of protein sedimentation equilibrium in detergent solutions without density matching. LVAD support increases LV collagen cross-linking and the ratio of collagen type I to III, which is associated with increased myocardial stiffness. Experiments with MOR KO mice and with DAMGO (MOR specific agonist) confirm that the effect of morphine on TLR4 mRNA in peritoneal macrophages is due to the MOR activation.

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Although these and other studies were consistent with predictions assuming superfluidity, proof of superfluid behaviour has been elusive. Downregulation of tumor necrosis factor receptors of macrophages by interferons and interleukin-1. Therapeutic intervention should be directed to patients with persistent conduction block, with the aim of eradicating the block and possibly minimising subsequent axon loss. Distinctive expression of neoantigenic C3(D) epitopes on bound C3 following activation and binding to different target surfaces in normal and pathological human sera. Early clinical differentiation is important, because lethal catatonia often requires neuroleptic treatment, and neuroleptic malignant syndrome necessitates immediate cessation of neuroleptics.

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In contrast, the 5-HT-ir fibers formed a dense network in both the dorsal and external cortices of the IC, while they were less abundant in the remaining subnuclei. By contrast, data from informal media are typically available in near real-time and could provide earlier estimates of epidemic dynamics.

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The PWV significantly faster in diabetics with microalbuminuria than in those without this findings. Gastric strongyloidiasis and infection by the human T cell lymphotropic virus type 1 (HTLV-1).

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Inconsistent grading of aortic valve stenosis by current guidelines: haemodynamic studies in patients with apparently normal left ventricular function. Multifunctional QD-based co-delivery of siRNA and doxorubicin to HeLa cells for reversal of multidrug resistance and real-time tracking.

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The trap combines tunable fields, homogeneous over most of the trap volume, with steep gradient fields at the trap boundary. Such an area determination of PAE implies that this method is less likely to be influenced by the early portion of a growth curve and therefore less dependent on the ability of a technique to detect a minimum bacterial density (sensitivity limit). The part of XDE-LE critical for somatic RNA clearance exhibits homology to zebrafish nanos1 and appears to be targeted by Xenopus miR-18 for somatic mRNA clearance. p21-deficient colon cancer cells continued to proliferate in the presence of mevastatin. to assess the efficacy of Debridase for treating BICS in an animal model.

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The differential functional activity of mAb CL203.4 and RR1/1 does not reflect differences in their affinity, because they display a similar affinity constant to lymphoid cells. Cervical and cervico-transsternal access was used, and surgery was performed to an extent determined by the pattern and extension of tumor. Leukocytoclastic vasculitis has not been previously reported as a complication of salmonella gastroenteritis and bacteremia. Guided bone regeneration for implant placement using absorbable collagen membranes: case presentations. The nature of the possible adsorbent and metal ion interactions was examined by the FTIR technique.

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The less homomorphic and smaller swelling/shrinkage of earlywood in radial direction is found to be caused by the presence of rays. cDNA cloning, using a mouse retina library or RT-PCR from rat, chicken, zebrafish, and human retina, was performed to determine the sequence of 5A11/Basigin transcripts.

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A very rapid recovery of granulocytes was observed in most cases. This review aims to update combined hepatocellular-cholangiocarcinoma with an emphasis on the pathological diagnosis, including the differential diagnosis and its diagnostic pitfalls, the possible cell of origin of this neoplasm, and its clinical outcome.

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Serum endostatin predicts tumor vascularity in hepatocellular carcinoma. The author reports clinical criteria of diagnosis of neuropsychic disintegration in the early ontogenesis of children (under 1 year of age and 1-3 years). Prolonged closure times must be interpreted in conjunction with a full blood count, von Willebrand factor (VWF) screen and other platelet tests. In cervical cancer, the rationale for the use of interferon is somewhat different in that this disease may be a manifestation of a virally induced proliferative lesion.

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The objectives of this study were to determine CSF shunt reinfection rates following initial CSF shunt infection in a large patient cohort and to determine management, patient, hospital, and surgeon factors associated with CSF shunt reinfection. Cytophotometric assessment of granulosa cell protein and nucleic acid levels during the estrous cycle in rats treated with T-2 toxin. The sister species shared more components of their call repertoire with each other than with the more distantly related C. Wip1-expressing feeder cells retain pluripotency of co-cultured mouse embryonic stem cells under leukemia inhibitory factor-deprivated condition. Appeal for the domestic pig as a preclinical model for neurodevelopmental research is increasing.

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Increased levels of CRP and MCP-1 are associated with previously unknown abnormal glucose regulation in patients with acute STEMI: a cohort study. In agreement with the previous studies on DNP-polyacrylamide, it was found that to be immunogenic, each of the FL-polymers had to exceed a comparable threshold value of molecular mass and of hapten valence. Difference in molecular properties between chicken green and rhodopsin as related to the functional difference between cone and rod photoreceptor cells. This study reviews the literature and summarizes the preferred vidian nerve exposure, recent technical refinements, and our current surgical approach. School readiness and CNS maturity: relation to psychophysical and psychosocial development and to early school achievement.

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These traction-screws were initially elaborated for rigid stabilization after sagittal ramus osteotomies such as Obwegeser-Dal Pont. Osteogenin does not impair normal lymphocyte blastogenesis at 6 months postsurgical challenge. In this article, I examine whether current research methodologies conform to the ethical guidelines enumerated by the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, and adopted into the federal regulations that protect research subjects. Polysomnographic (PSG) studies were performed in 4 of the 7 patients and in 2 asymptomatic carriers of the mutation. Renal and systemic-hemodynamic response to isovolemic exchange transfusion with hemoglobin cross-linked with bis (3,5-dibromosalicyl) fumarate or albumin.

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T-tests were used to analyze person-level differences in service use before and after delivery. Different mechanisms for collecting and managing funds, and for paying for services are discussed. Our results suggest that inflammation-associated decreased galactosylation of IgG combined with high expression MBL2 genotypes are involved in the pathophysiology of RA. We present a case of delirium due to amitriptyline overdose, which resolved rapidly following initiation of the cholinesterase inhibitor donepezil.

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The regions that differ among orf2, map1, and omp1b correspond to previously identified variable sequences in outer membrane protein genes of E. Pollen-starved bees supported significantly smaller populations of the parasite.

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The contribution of interleukin (IL)-6 signaling in obesity-induced inflammation remains controversial. These results demonstrate that the brain levels of NGF and BDNF are dependent on the dietary content of tryptophan.

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Characterization of a high-affinity antiserum specific for the amino-terminal sequence of human parathyroid hormone. Computational modeling of cell deformation in response to fluid flow showed the percentage of cells exceeding a critical threshold of deformation correlated with cell detachment experimentally and the majority of these cells were of a bridging morphology (cells stretched across pores).

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In 21 out of 24 patients with clinically diagnosed phaeochromocytoma in the University Medical Hospital, Groningen in 1983-1990, MIBG scintigraphy provided accurate localization, while in 16 out of 18 patients with phaeochromocytoma who underwent CT scanning a correct localization was obtained. Simultaneous determination of a novel antifibrotic agent and three metabolites in human urine by LC-MS/MS.

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While in healthy older adults preserved recollection for pictures could lead to the picture superiority effect, in patients with MCI it is most likely that the picture superiority effect is a result of spared conceptually based familiarity for pictures, perhaps combined with their intact ability to extract and use gist information. Tetanus immunization programs could be more successful if tetanus were a clearly marked target for the Aymara, Quechua and Tupi-Guarani people, and vaccinators were sensitive to their cultural perceptions. There are many regimens for cancer chemotherapy, and thus information management is complicated. It has been suggested that pericentric inversions of chromosome 2 increase the risk for spontaneous abortion but do not increase the risk for unbalanced recombinant offspring. Actual versus actuarial analysis for cardiac valve complications: the problem of competing risks.

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The level of immunoglobulins in sick children with thymic hyperplasia. Coexistence of glutamate and substance P in dorsal root ganglion neurons of the rat and monkey. Preparing medical students to practice medicine effectively in managed care settings will require focused attention on managed care issues in the medical school curriculum and the combined efforts of academic health centers and managed care organizations. Theophylline and forskolin showed similar effects as the beta-adrenergic stimulants. These simulations show that the mean square observation error is 0.58 when the proposed observer is implemented in a solid-waste anaerobic digestion process to estimate the evolution of biomass concentration.

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By using a three-dimensional collagen gel (3D-CoG) supplemented with fibrinogen (Fib) we studied the growth behavior of S. To our knowledge, this is the first report describing sequencing of targeted genomic regions in any livestock species using groups with divergent phenotypes for an economically important trait.

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The data are consistent with the notion that the exceptional diversity of the HIV-1 genome results from error-prone reverse transcription. Mutagenesis and chimeric genes define determinants in the beta subunits of human chorionic gonadotropin and lutropin for secretion and assembly. Hepatic artery sectorial enhancement as a sign of acute portal thrombosis.

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The Coomassie-blue staining of amelogenins from both species revealed very similar patterns, which indicates a rather common processing, although developed at different rates. The LDW process presented in this paper is an etching- and template-free nanopatterning technology based on nanoscale wrinkling phenomenon.

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Determinants of the partition of renal ammonia production between urine and venous blood in man with metabolic acid-base disturbances. In the course of infection, the domains must separate to expose the binding site for TolA on domain N1. Surgical management of acute right lower-quadrant pain in pregnancy: a prospective cohort study. Increasing numbers of reports concerning diabetes, ketoacidosis, hyperglycaemia and lipid dysregulation in patients treated with second-generation (or atypical) antipsychotics have raised concerns about a possible association between these metabolic effects and treatment with these medications. Relaxation behavior therapy as sole treatment for mild hypertension.

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We determined the natural history and outcome of adolescents with low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL). Abciximab reduces major adverse cardiac events (MACEs) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). We describe a modification of the tetracycline-controlled expression system that facilitates the rapid identification of tetracycline-sensitive clones. Epidemiological and geographical findings of prevalence of MS indicate the involvement of an infective agent.

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This led us to hypothesize that expression of some of the 41 genes contributes to tumor radioresistance and clinical recurrence. The origin of this neoplasm, the reasons for its rarity at this site, and the range of its biological behavior are discussed in relation to the clinical manifestations of this case. We therefore suggest GLP-1 as a true incretin hormone and enterogastrone in humans. Using the true acceleration and displacement vector (orientation and magnitude), rather than the three separate components, may permit more accurate cardiac event detection. The animals were decapitated at 0.5 h or 1 h after naloxone injections and their brains analysed for monoamine concentrations by HPLC-ECD.

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Transplantation of human neural stem cells (hNSCs) is emerging as a viable treatment for stroke related brain injury. The papers in this issue reflect the breadth and depth of approaches being adopted to address this issue.

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Influence of reinfused UV-irradiated autologous blood on histochemically demonstrated enzymes in dog muscles The engineered element, iTto (inducible Tto1), is a novel tool for analysis of retrotransposition in plants.

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Free, and not total, 1,25-dihydroxyvitamin D regulates 25-hydroxyvitamin D metabolism by keratinocytes. To compare cephalocondylic intramedullary nails with extramedullary implants for extracapsular hip fractures in adults. We present a case of villous adenoma of the prostatic urethra, without malignant transformation.

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The antiserum revealed ChAT immunoreactivity in the motoneurons and terminal-like structures in the neuropil of the ventral horn in cryostat sections of the cervical spinal cord of the rat. Protease activation has also been implicated in necrosis, but its role in this cell death process and the identity of the proteases involved and their substrates, are unknown.

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Up-regulation of Duffy antigen receptor expression in children with renal disease. We aimed to determine the incidence of recurrence of VTE in relation to clinical risk factors and standard laboratory testing for heritable thrombophilic defects. Among vegetables, spinach had the highest antioxidant capacity in the TEAC and FRAP assays followed by peppers, whereas asparagus had the greatest antioxidant capacity in the TRAP assay. Since changes in weight will reflect choices with respect to diet and activity, the extent to which overweight and obesity rates change with years in Canada may reflect the extent to which immigrants interact with or are influenced by members of their ethnic group who reside in the same area. Amino acid sequences of peptides from a chymotryptic digest of a urea-soluble protein fraction (U.S.3) from oxidized wool.

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Although several studies have reported on the use of children as donors for peripheral blood progenitor cells (PBPC), no specific characteristics have been identified as predictors of PBPC collection in this population. Many strategies for repairing injured myocardium are under active investigation, with some early encouraging results. Polyuria without a compensatory increase in water consumption was observed in treated rats. Preliminary comparisons between DVA scores of a nonselect sample of college students and those of a small group of college athletes indicated that the athletes were not very different from the nonselect group and would also benefit from training on the task. The N-methyl-D-aspartate receptor (NMDAR), which is one of the glutamate receptors, is considered to have a close relation to synaptic plasticity in the developing brain.

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Correlation between shrinkage and infection of implanted synthetic meshes using an animal model of mesh infection. Methanol did not adsorb at either interface in detectable quantities, while acetonitrile adsorbs at the octadecylsiloxane- and quartz-solution interfaces in a concentration-dependent manner and is well ordered at the interface.

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Color selectivity of neurons in the inferior temporal cortex of the awake macaque monkey. The aims were to evaluate the frequency and nature of errors in medication when patients are transferred between primary and secondary care. Stabilities of leucine zipper dimers estimated by an empirical zitromax presentacion suspension free energy method. In this report, we describe the case of a gentleman in whom bilateral profunda femoris artery aneurysms were detected during angiography to investigate his intermittent claudication.

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Immune complex tyrosine kinase assay of PDGF receptor beta immunoprecipitates from lysates of mesangial cells treated with PDGF showed no inhibitory effect of BMP2 on PDGF receptor tyrosine phosphorylation. Although levels of the cell death gene product Nur77 were equivalent, additional studies showed that mutant cells expressed Nur77 predominantly in the cytoplasm following TCR engagement, quetiapine abuse pdf merge while parental cells displayed a nuclear translocalization of Nur77.

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One explanation may be the different definitions of outcome used. Antiinflammatory activity of a new preparation Artrofoon (antibodies against tumor necrosis factor-alpha in ultralow doses) and nonsteroid antiinflammatory drug diclofenac in patients with rheumatoid arthritis was compared in an open randomized trial. A prospective database of patients undergoing parathyroidectomy was analyzed for thyroid pathology discovered by ultrasound. In view of the small number of patients, the clinical forum valium valrelease diazepam generics relevance of TENS in patients in a midstage of AD remains to be confirmed in a larger group, after which more definite conclusions about the stage-dependency of TENS in AD can be drawn. Furthermore, we show that CGI-58 is necessary for maximal TH1 cytokine signaling in the liver.

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Differential patterns of local gene regulation in alzam pills crush lesions of the rat optic and sciatic nerve: relevance to posttraumatic regeneration. A total of 33 men and 19 women developed the disease (including 3 children under 14 years of age). Multi-residue method for fast determination of pesticide residues in plants used in traditional chinese medicine by ultra-high-performance liquid chromatography coupled to tandem mass spectrometry. However, sublingual NTG (0.15-0.60 mg) administration caused significant relaxation of partially constricted veins. Using a testing apparatus, the range of internal and external humeral rotation was assessed in an arc of glenohumeral elevation in the scapular plane with steps of 15 degrees in six isolated shoulder joint specimens.

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The objective of this study was to examine whether a simple, brief integrated approach to depression and type 2 diabetes mellitus (type 2 diabetes) treatment improved adherence to oral hypoglycemic agents and antidepressant medications, glycemic control, and depression among primary care patients. Additional approaches employing stem cells to identify and mutate putative developmental genes are coming into use. It appears that any direct venodilator phorpain gel dosage forms effects of verapamil in conscious rats are masked due to reflex activation of the autonomic nervous system. To determine serum levels of TNF-beta and soluble TNF-R in patients with primary highly malignant bone tumours.

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However, the clinical spectrum of WNV-associated weakness has not been described. In addition, in a double-blind, placebo-controlled multicenter trial, galectin-9 levels were measured in the sera of 90 infants with atopic dermatitis who valzaar tablet magazine received hydrolyzed formulae with or without GF/Bb. Single-molecule level observations with scanning tunneling microscopy monitor the successive aufbau of structures with increasing complexity.

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A contrast study in the colon revealed a sigmoid colon stricture. It is indispensable to join efforts in coordinated networks to define, as soon as possible, the best treatment and the best time to start it. In addition, it has been zozo for sale in gauteng education proposed that biomarkers may be useful in predicting subsequent necrosis in SAP. In three experiments students were asked to perform a Stroop-like task. p53 deficiency does not affect the accumulation of point mutations in a transgene target.

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Cytochrome b5 at a ratio of 1:1 or 2:1 to P450IIB1 had no significant effect on the metabolic activities and profiles of NNK. The effect of methylphenidate (MPH) on inhibitory control as assessed by the stop task in children with attention-deficit/hyperactivity disorder (ADHD) could be influenced by task difficulty and may be mediated by attention. Protein kinase C-and ras-dependent activation of c-jun gene by human papillomavirus type 11 E5a oncoprotein. This MCA has been uricon medication interactions previously characterized as being primarily due to fibronectin fragments. Auditory spatial function was assessed in six patients who had undergone unilateral cerebral hemispherectomy for the relief of intractable epilepsy.

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The results obtained show that cyclosporin A potentiates the toxic effect of alloxan on the pancreatic B-cells. Report about experiences with developing a perinatal center step by step an the University of Leipzig, primarily directed to improve the results of premature labour, then expanded by intensive diagnostics and treatment and uniform documentation of all risk pregnancies. The diverse functions of menin interactors suggest roles for menin in multiple biological pathways. Measurement of cutaneous vibrotactile thresholds may be useful for assessment of the functional australia dove si trova medjugorje integrity of the somatosensory system. Stress incontinence as a valid nursing diagnosis has remained clinically untested since its approval as a nursing diagnosis in 1986.

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Gold-thioglucose (GTG) induces lesions in the ventromedial nucleus of the hypothalamus, resulting in hyperphagia and obesity. The epitope of the Fab fragments of MAb 2C2 overlapped the BmAPN1 binding site, whereas the epitope of the Fab fragments of MAb 1B10 did not overlap ivermectin tablets for humans uk tv but was located close to the binding site.