Zedem is used to treat insomnia (trouble sleeping). It belongs to the group of medicines called central nervous system (CNS) depressants, which slows down the nervous system. Zedem will help you get to sleep faster and sleep throughout the night. In most cases, sleep medicines should only be used for short periods of time, such as 1 or 2 days, and for no longer than 1 or 2 weeks.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Tablet
• Tablet, Extended Release
• Spray

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They were subjected to thermal therapy that consisted of a far-infrared ray dry sauna at 60 degrees C and postsauna warming. 91 users completed a survey specifically designed to know their evolution at different follow-up periods (1, 3, 5 or 10 years after their exit from the TC): socio-demographic, psychoactive substance use, other variables related to the stay at the TC.

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Appreciation of this cross-reactivity, and of the evolutionary conservation of the epitope, as well as its sensitivity to denaturation, has led to our working hypothesis that F4 binds to a conformational epitope present on several polypeptides that may be most perfectly represented by some aspect of the catalytic domain of tyrosine protein kinases. The female patient was diagnosed with idiopathic PAH at the age of 7. A technique for the detection of calcium deposition in human larynges, formerly used only in staining bony and cartilaginous tissue of small vertebrates, is described.

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This study aimed to examine the hypothesis that PLV would attenuate the production of local and systemic cytokines in an immature piglet model of ALI induced by oleic acid (OA). Electrophoresis was accomplished in 9 min, separating a whole histone preparation into its components in the following order of decreasing mobility: (MHP) H3, H1 (major variant), H1 (minor variant), (LHP) H3, (MHP) H2A (major variant), (LHP) H2A, H4, H2B and (MHP) H2A (minor variant), where MHP is the more hydrophobic component and LHP is the less hydrophobic component. First-order rate constants for the pH-independent hydrolysis of 1-benzoyl-1,2,4-triazole in aqueous solution at pairs of such isochoric temperatures show no unique features. Different patterns of signal enhancement between the pulmonary vessels and parenchyma are shown in the perfusion images acquired at different TIs. We find that all four rNTPs can be incorporated opposite the CPD lesion, and that this process affects translesion synthesis.

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A comparison of atropine and patching treatments for moderate amblyopia by patient age, cause of amblyopia, depth of amblyopia, and other factors. A membrane-bound cytolytic pore-forming protein (N-PFP) produced by the pathogenic ameboflagellate Naegleria fowleri was characterized.

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Protective efficacy of a Treponema pallidum Gpd DNA vaccine vectored by chitosan nanoparticles and fused with interleukin-2. The concentrations of osteocalcin were significantly higher in the first trimester of physiological pregnancy in comparison with nonpregnant women and with second and third trimesters of pregnancy. Samples of plain, strawberry, apple-pear and forest-fruit flavored probiotic fermented milk were analyzed both by standard methods and by the potentiometric sensor array.

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Chemotherapy-related and radiotherapy-related acute toxicity was relevant but tolerable. This study determined the effects of long-term chemical sympathectomy with guanethidine (GN) on the mechanical properties and composition of the distal abdominal aorta in Wistar rats. In the patients the study was performed within 48 hours of cardiac catheterisation.

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Our hypothesis was that children who experience continuous weight gain at a given rate will have better average forced expiratory volume in 1 second (FEV(1)) and change in FEV(1) than children who have weight gain patterns that deviate from this rate, even when total weight gain seems adequate. Adsorption results in a strongly deformed macrocycle and a quenching of the first NEXAFS resonance in the nitrogen edge suggesting electron transfer into the LUMO. A controlled trial in intensive care units of selective decontamination of the digestive tract with nonabsorbable antibiotics. Percutaneous sonographically guided fine-needle puncture and drainage of pyogenic abscesses

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These results show that a peptide homologue of p53 is sufficient to induce p53 dependent cell death in cells overexpressing MDM2, and support the notion that disruption of the p53-MDM2 complex is a target for the development of therapeutic agents. C-reactive protein and nitric oxide level in patients with white coat hypertension.

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Labor and delivery management of multiple gestations remains controversial. However, RhoA was activated only at the leading edge in MDCK cells migrating as a monolayer sheet. These results suggest that norepinephrine facilitates LHRH pulse generator activity through both alpha- and beta-adrenergic-receptors, and that the action of opioid peptides on it requires an alpha-adrenergic receptor-mediated mechanism.

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The medical records of 27 children and adolescents with a minimum follow-up of 6 months were retrospectively evaluated with respect to seizure status, anticonvulsant outcomes, and subjective results. Using these indications before surgery in patients who underwent hepatectomy between 2004 and 2008, we compared the prevalences of postoperative complications in the the two groups of patients. Effect of splenectomy upon the growth of B16-F10 melanoma and its relation to the interferon system. The serum specific IgE to cefaclor-HSA conjugate was detected using enzyme-linked immunosorbent assay (ELISA).

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In some cases, deliberate subtotal tumour resection is useful to avoid severe neurological damage with sufficient tumour control and a valuable progression-free survival. A study on clinical attachment loss and gingival inflammation as etiologic factors in pathologic tooth migration. To define the structure-function relationship, we have made a number of mutants of human granulocyte colony-stimulating factor (hG-CSF) by in vitro mutagenesis. Effect of vitamin K1 on glucose-6-phosphate dehydrogenase deficient neonatal erythrocytes in vitro.

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Images of simulated semiflexible polymers with known bending and torsional rigidity are analyzed to validate the method. Reported differences concerning the role of cathepsin D as a prognostic marker may be related in part to the methodology used and the employment in the assays of antibodies prepared to different portions of the molecule.

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Currently, the disease still progresses in the population, but survival increases hopefully. Massive suprachoroidal hemorrhage with central retinal apposition. In some cases an endocrine disorder may be suspected based on dermatological findings during hair loss evaluation. A 35 year old male with thrombotic obstruction of the inferior vena cava superimposed on a membrane was treated by prolonged (48 hours) infusion of streptokinase followed by balloon membranotomy. Cloned granulocyte colony-stimulating factor (G-CSF) was recently shown to enhance the growth and differentiation of normal granulocyte progenitor cells in vitro.

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We conclude that the glans penis of the rat contains a sensory receptor complement that is generally similar to the human glans penis but is unlike the glabrous and hairy skin. It has features that make it unusual and robust when compared with other learning paradigms. A murine monoclonal antibody, MoAb HMSA-5, against a melanosomal component highly expressed in early stages, and common to normal and neoplastic melanocytes. Most articular symptoms were improved, probably as a result of corticosteroid therapy.

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Recently, a new generation of mTOR inhibitors, which compete with ATP in the catalytic site of mTOR and inhibit both mTORC1 and mTORC2 with a high degree of selectivity, have been developed. Considerable interpatient variability has been observed in both plasma and cerebrospinal fluid 6-mercaptopurine levels. Supramolecular self-assembly induced graphene oxide based hydrogels and organogels. To evaluate the occurrence of these lesions in a series of mixed tumors, and determine its histomorphological characteristics.

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An easy-to-implement approach for analyzing case-control and case-only studies assuming gene-environment independence and Hardy-Weinberg equilibrium. Eighty samples of MEE were collected from patients with otitis media with effusion. HepG2 cells were cotransfected with pcDNA3.1(-)-complete S and pSV-lacZ. Appreciation of the anti-inflammatory actions of theophylline at low serum concentrations has revived the interest in this drug, but its cardiac side effects remain a concern. However, small differences existed between the antibodies in the actual minimal requirement for C- and N-terminal parts of this epitope.

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Differences in the shape and slope of the acromion, anterior acromial spurs and inferior protruding acromio-clavicular osteophytes decrease the volume of the subacromial space, leading to impingement. Improvements needed for new QSARs and tools for developing and using QSARs are discussed. A review of the literature on measuring the concept of stigma related to caring for a relative with mental illness yielded no instrument appropriate for use in Jordan. Our model may also be useful in etiologic and epidemiologic studies of ASD, because different causes of ASD are likely to follow different developmental trajectories along these 3 parameters. Animal and human myocytes demonstrate significant swelling and reduced contractility during exposure to stress (metabolic inhibition, hyposmotic stress, or hyperkalemic cardioplegia), and these detrimental consequences may be inhibited by the addition of diazoxide (adenosine triphosphate-sensitive potassium channel opener) via an unknown mechanism.

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The structure of OmpK36 closely resembles that of the search model. To establish a HPLC method for measuring tashinone II(A) concentration in rabbit plasma and study the pharmacokinetics of tashinone II(A) -loaded polylactic acid nanoparticles and tashinone II(A) injection in rabbits. Re: Measurement of defect angle in superior semicircular canal dehiscence. Radial longitudinal deficiencies with hypoplastic/absent thumbs and cutaneous syndactyly of the most radial digits. The leading cancer sites that generate most productivity losses are highly preventable or can be diagnosed early or are related to tobacco consumption.

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Nosocomial transmission of TB, and particularly drug-resistant TB, is a potential risk that may be undetected. The current study aimed to evaluate whether UAL facilitates pelvic laparoscopic lymphadenectomy in obese subjects. Combined effects of fasting and diet on interferon production and virus replication in calves infected with a vaccine strain of infectious bovine rhinotracheitis virus. A time- and dose-dependent translocation of PKC from the cytosol towards the membranes was observed at oleate concentrations that fell within the range of concentrations reached under several physiological conditions. The delivery of critical care is no longer limited to the intensive care unit.

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All of these are important aspects of cancer progression, but the relationship between Eph receptors and cancer is complex and not fully understood. Accumulating evidence of muscle mitochondrial dysfunction in insulin-resistant states has fuelled the notion that primary defects in mitochondrial fat oxidation may be a contributory mechanism. Occurrence of neurocalcin, a calcium-binding protein with three EF hand motifs, was examined immunohistochemically in the rat olfactory epithelium and vomeronasal organ epithelium.

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Assessing the impact of Medicaid managed care on TB activities in local health departments. Croup is the most common form of airway obstruction in children. Two-dimensional infrared correlation spectroscopy study of sequential events in the heat-induced unfolding and aggregation process of myoglobin.

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This phenomenon could be in part responsible for increased adhesion of granulocytes to endothelial cells and could facilitate tissue infiltration after endurance exercise. Met-PET guidance allowed a total resection of Met uptake in 17 cases that were considered total tumor resections because the operative margin left in place contained nontumor tissue. Effect of dietary supplementation of organic chromium on performance, carcass traits, oxidative parameters, and immune responses in commercial broiler chickens.

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Ultrasound and magnetic resonance imaging confirmed a splenic tumor, which showed no uptake on 18F-fluorodeoxyglucose positron emission tomography. Re: HLA-D region epitopes associated with juvenile arthritis:recognition by alloreactive T cell clones and alloantisera. In contrast to their effects on apomorphine-induced yawning, nifedipine and Bay K 8644 had no effect on apomorphine-induced penile erection.

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Regional sex differences were observed with pronounced thinning in the left paracentral lobule and right posterior cingulate in male and female patients respectively compared to same sex controls. Diagnosis and management of acyanotic heart disease: part II -- left-to-right shunt lesions. AKT-modified autologous intracoronary mesenchymal stem cells prevent remodeling and repair in swine infarcted myocardium.

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However, these impacts of mutation and drift are apparently attenuated by selection on amino acid composition at high-expression genes. Measurement of thermal neutron fluence distribution with use of 23Na radioactivation around a medical compact cyclotron. Pathologically they were all well differentiated hepatocellular carcinoma and there were no differences between hypo- and hyper-echoic tumors.

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Estimation of pneumonitis risk in three-dimensional treatment planning using dose-volume histogram analysis. A Tzanck preparation obtained from an early lesion was positive for multinucleated giant cells.

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We studied one case of atypical polypoid adenomyoma of the uerus immunohistochemically using antisera against keratins, vinentin, S-100 protein, desmin and actin. The Minimal Contact Education for Cholesterol Change study is used as an example of the use of this strategy.

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Histological examination of both testes showed germinal aplasia and the proliferation of Leydig cells. An immunohistochemical, histochemical and ultrastructural study. The results support the concept that factors which prevent persistent infection in euthymic rats act early after virus inoculation and may include cellular immunity. Here we combine a variety of in situ hybridization techniques that make the physical mapping of DNA clones to mouse chromosomes much easier.

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Effects of organic forms of zinc on growth performance, tissue zinc distribution, and immune response of weanling pigs. Repeated amphetamine use produces an enduring sensitization of brain dopamine (DA) systems and behavior. This paper shows that an advanced degree of left ventricular dysfunction and the preference frequent or complex ventricular arrhythmias appear to be major predictors of total and sudden mortality among patients with congestive heart failure. There were 223 women in the group with a 2-h value of 8.0 to 8.9 mmol/l in the OGTT.

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To establish whether time, pressure, or volume is the most reliable indicator of adequate pneumoperitoneum and, hence, the best parameter to use for safe trocar entry. The possible mechanism of traumatic stricture formation at such a rare anatomic location and the therapeutic options are reviewed.

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Corticoreticular fiber systems were examined in adult albino and hooded rats using anterograde transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) and anterograde degeneration. They are involved in different presynaptic and postsynaptic functions, including synaptic vesicle exocytosis for neurotransmitter release, vesicle endocytosis for synaptic vesicle recycling, as well as postsynaptic receptors and proteins constituting the PSyD. House made red blood cells are costless than commercially available reagent red blood cells mainly due to the simplified method of preparation.

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Activation of the trigeminal medullary dorsal horn during voluntary diving in rats. Risk of ischemic stroke associated with functional thrombin-activatable fibrinolysis inhibitor plasma levels. LC-OCD has the capacity to provide a fingerprint of WEOC, which allows analysis of the various fractions present.