Onapil is used to prevent and control seizures. This medication is known as an anticonvulsant or antiepileptic drug. It is also used to treat panic attacks. Onapil works by calming your brain and nerves. It belongs to a class of drugs called benzodiazepines.

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Little TNF doses (0.025-0.25 ng) inhibit angiogenesis induced by the angiogenic factor received from the Lewis carcinoma. HMB-45 special staining could be regarded as a diagnostic criterion for HAML.

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Endovascular treatment of a blunt traumatic abdominal aortic injury with a commercially available stent graft. The prevalence of bacteria and fungi causing pneumonia in association with oral biofilm bacteria were determined using detection culture plates.

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SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA. Maternal and teacher ratings of child behavior were obtained with the parent and teacher versions of the Achenbach Child Behavior Checklist.

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Dau c 1.01 and Dau c 1.02-silenced transgenic carrot plants show reduced allergenicity to patients with carrot allergy. Double bundle augmentation has advantages with regard to posterior and rotational stabilities as well as ligament stress in comparison with other reconstruction methods, especially following secondary deficiencies in the reconstructed grafts. Results indicate that analysis of combined NGS and microarray data is feasible, but successful detection of DEGs may depend on careful selection of algorithms as well as on data normalization and pre-processing.

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This nuclear rearrangement could be connected with differentiation-related heterochromatinization of the amplified BCR-ABL locus, as demonstrated by increased histone H3(K9) dimethylation and decreased H3(K9) acetylation of B3A2 breakpoint. Neonatal adenovirus infection: a case report with in situ hybridization confirmation of ascending intrauterine infection.

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Deoxynivalenol (DON) and other ribotoxic trichothecenes cause immune stimulation and suppression in leukocytes by upregulating gene expression and apoptosis, respectively. The impact of pumped water from a de-watered Magnesian limestone quarry on an adjacent wetland: Thrislington, County Durham, UK. Forty-six first-year medical students completed the Physician Values in Practice Scale (PVIPS) during their first and fourth years of medical school.

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This study was conducted to investigate the role of humoral factors in pancreatic alterations induced by obstructive jaundice (OJ) in rats. Mice that were immunocompromised due to LP-BM5 virus infection were highly susceptible to acute (lethal) infection with herpes simplex virus type 1, whereas their immunocompetent littermates were not. Functional effects of a natural polymorphism in the transcriptional regulatory sequence of HLA-DQB1. Alternative splicing (AS) of pre-mRNA is utilized by higher eukaryotes to achieve increased transcriptome and proteomic complexity.

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Antibiotic resistance, plasmid profiles and plasmid structures were examined in nasal Staphylococcus aureus collected from a random sample of normal individuals in the mid 1960s and from women at an antenatal clinic in 1989. The aim of this review is to summarize the clinical and health economic data of FP and its modified version. This report looks at some of the clinical trials that are ongoing or planned in the treatment of pulmonary disease in CF. RT-PCR was used to clone the CYP2E1 gene in human embryonic nasopharyngeal epithelial (HENE) cell, the transformed nasopharyngeal epithelial cell line (7,429), and the nasopharyngeal carcinoma cell line (HNE1). To investigate alternative mechanisms, we examined whether PKG affects the phosphorylation of E26-like protein-1 (Elk-1), a SRF/myocardin transcription antagonist.

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Novel cardiovascular disease risk factors such as PAT may contribute to ethnic disparities in susceptibility to development of coronary atherosclerosis. By means of alkaline phosphatase (ALP) activity and osteocalcin ELISA assay, I have shown that myricetin exhibits a significant induction of differentiation in the human osteoblast-like cell line MG-63. Oligodendrocytes are the cells responsible for the formation of myelin in the central nervous system. The ratios of nasal width to lower face height, as well as nasal width to nasal height, were found to differ significantly only between open bite and normal females, being higher in the latter group. Previewing scenes briefly makes finding target objects more efficient when viewing is through a gaze-contingent window (windowed viewing).

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Using an available model system, we were able to put forward some candidate regions that may be involved in neuroblastoma. Acceleration of protein synthesis by insulin was not associated with an elevation of cAMP.

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Even though most US- and Canadian clinics use mediastinoscopy staging preoperatively because of differing sensitivity in CT. Research on the morphology of the jugular foramen: presence of an accessory canal for the glossopharyngeal nerve in the skulls of newborn infants The anvil was passed transgastricly and reference biopsies were taken from the gastrotomy in the corpus of the stomach. The main cause of this is cardiovascular abnormalities (aortic root dilatation, aortic dissection, rupture of the aorta, other cardiac abnormalities). A retrospective study of the results of neoplastic cord compression was undertaken to determine the effectiveness of surgical treatment and to assess quality of life in patients undergoing extensive procedures with potential morbidity.

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Directional atherectomy (DA) has become popular in some centers to remove atherosclerotic plaques in femoro-popliteal lesions. However, when the entire pattern of results was examined, a large difference between compatibility and congruence were also seen, which implies that there is at least one important difference between the two phenomena. Sun-exposure- and aging-dependent p53 protein accumulation results in growth advantage for tumour cells in carcinogenesis of nonmelanocytic skin cancer. Logistic regression showed the same statistically significant association of distance to HFs, even when controlling for age and gender of the child, ratio of nets to children in household, community net possession and use, and household material wealth.

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Judges, CASAs, and guardians ad litem provided the data for the study. Urban youth (aged 14-24 years) were invited to participate in focus groups in which a trained focus group facilitator used a survey and a structured guide to elicit responses regarding the foregoing objective. The data reviewed here indicate that the melanocortin system has been strongly conserved during vertebrate evolution and that alpha-MSH is produced locally in birds to act as an autocrine/paracrine hormone.

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Knockdown of metallothionein 1 and 2 does not affect atrophy or oxidant activity in a novel in vitro model. Survey of contact lens-wearing habits and attitudes toward methods of refractive correction: 2002 versus 2004. The observations are discussed in relation to what is known of the function of SP in the heart and of the distribution of sympathetic and parasympathetic nerve fibers in the conduction system.

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Proteomics of snake venoms from Elapidae and Viperidae families by multidimensional chromatographic methods. Clusters of genes exhibiting distinct expression patterns within specific tissues were identified. RS virus rarely causes meningitis, but a percentage of RS-virus-infected infants exhibit symptoms such as seizure and disturbance of consciousness. We report an autopsy case of amyotrophic lateral sclerosis (ALS) clinically diagnosed as spinal progressive muscular atrophy (SPMA). Information about morphologic changes of PSL as reported by the patient is a useful extension of the ABCD rule for dermatoscopy.

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We found that the language of the hemispherectomies paralleled that of their MLU matches with respect to the specific morphosyntactic characteristics of each stage. Healthcare reform and the hospital industry: what can we expect? After a complete cDNA clone of the Sendai virus NP gene was expressed in Escherichia coli, deletion constructs were used to generate a series of overlapping NP fragments deleted at their C termini.

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The skin colour parameters showed a higher red intensity value in menopausal women who had been treated for at least 1 year. With this model the appropriate contribution of the historical studies can be determined.

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What can be done about the yo-yo effect? piscicola JCM5348 did not prevent the growth of the pathogen, except at 4 degrees C. Evidence for cardiac loading (increased preload and afterload) and LV systolic (in the first trimester) and later diastolic dysfunction was observed.

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The GFAP-positive astrocytes proliferated much more numerously in the severely demyelinated white matter. The skin pressures of 16 different positions located in four heights and four directions of the lower limb were measured and recorded by FlexiForce interface pressure sensors (Tekscan, Inc., Boston, MA, USA) and a multichannel measuring system. The monoclonal antibodies identified another shared epitope, which is most likely conformational and a unique Cry j 1 epitope that may be the previously recognized glycopeptide IgE epitope.

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Bacteremia is associated with high short-term mortality, but also a sign of severely curtailed long-term prognosis, especially in patients with low functional capacity, low serum albumin, high serum creatinine, nosocomial infections, malignancy, inappropriate antimicrobial treatment, and septic shock and in elderly patients. Only case reports or open-labeled trials have been conducted with alpha-adrenergic agents, other antidepressants, atypical antipsychotics, and antiepileptic agents. Life history traits were similar throughout, although differences in the breeding season were apparent between populations on the Pacific coast, and in the Seto Inland Sea and the Ryukyu Islands. Results of this study show differences across Europe in the extent to which national pandemic policy and pandemic plans have been integrated with public health laws. These results suggest that afferent activity of the intact L4 spinal nerve aids in the development of mechanical allodynia in the SNL model of neuropathic pain.

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The aim of this study was to evaluate whether IFN prevents the development of HCC in patients with chronic hepatitis C. Thus, MT(1) receptor was localized exclusively at the basal side of the cell acini, supporting the hypothesis that this receptor is activated by the pineal-synthesized melatonin.

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Immunostaining and quantitative image analysis were applied to ethanol-fixed and paraffin-embedded tissue obtained at transplant in patients with CF or COPD, or postmortem in the control group. This study was designed to investigate the relationship between accuracy and speed for robot-assisted surgical skills.

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Schwannoma-derived growth factor (SDGF) and amphiregulin (AR) are members of this family. We hypothesized that this may be responsible for the association of current STI pathogens and HIV in women. Neurotransmitter interactions in psychotropic drug action: beyond dopamine and serotonin. In the present study the effect of the globular domains (collagenase-resistant domains) of type XII and XIV collagens (XII-NC-3 and XIV-NC-3) on the migration of fibroblasts into the reconstituted type I collagen gel was investigated. Measures of obesity included body mass index, waist circumference, and waist-to-hip ratio.

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The only clinically significant benefit from the use of routine EFM was in the reduction of neonatal seizures. Immunohistochemical double-labellings of luteinizing hormone-releasing hormone and neuropeptide Y, serotonin, tyrosine hydroxylase and dopamine-beta-hydroxylase, were performed in the preoptic area at the level of the organum vasculosum laminae terminalis.

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On the other hand, BB/W rats had significantly lower 48hr thyroidal RAIU than normal Wistar rats. The lactating rats that had been treated with dexamethasone showed increased initial avoidance latency when compared with lactating rats treated with vehicle.

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Fasting plasma glucose (FPG) and serum lipase levels were examined for endocrine and exocrine pancreatic functions, respectively. This results in an increase of renal blood flow and, at times, in an even greater rise of glomerular filtration rate (GFR). To assess the role of interleukin-1 beta (IL-1 beta) and tumour necrosis factor alpha (TNF alpha) in the physiological host defence mechanisms against malignancies, the production of these cytokines in sera, ascitic and cyst fluids and in the tumour tissues of patients with benign or malignant ovarian tumours was studied. Various semaphorins can either promote or inhibit tumor progression through the promotion or inhibition of processes such as tumor angiogenesis, metastasis and tumor cell survival.

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The labeled cells in the superior colliculus were located within the deep part of stratum griseum superficiale and the superficial part of stratum opticum, and were composed of multipolar cells, vertical fusiform cells and horizontal cells. Trastuzumab-mediated antibody-dependent cellular cytotoxicity against esophageal squamous cell carcinoma. Bisphosphonate remains highly localized after elution from porous implants. The results indicated that males had a higher rate of comorbid substance abuse/dependence, while females had a higher rate of comorbid bulimia nervosa.

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The expression of K5 was analyzed by reverse transcription polymerase chain reaction (RT-PCR) and immunohistochemistry. Treatment of mouse blastocysts with either TGF-alpha or TGF-beta results in the increased expression of the b subunit of the F0ATPase. Differential expression of equine myosin heavy-chain mRNA and protein isoforms in a limb muscle. Furthermore, nausea was associated with sevenfold to 16-fold increases in plasma pancreatic polypeptide concentrations (mean increase, ninefold), with no change in plasma levels of vasoactive intestinal polypeptide or substance P. Gender differences in the effects of haloperidol on avoidance conditioning in mice.

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In particular, a significant difference in the changes in HVA was demonstrated between the two groups. Differential thermal analysis (DTA) and thermogravimetric analysis (TGA) were used to verify the thermal degradation temperatures of these materials and to quantify the AgBG coatings on the sutures. Chemokines are a family of low-molecular-weight proteins essential to the directed migration of cells under homeostatic and pathological conditions. New substituted cyclopropane probes were used with very fast ring-opening rate constants and other desirable attributes, such as the ability to discriminate between radical and cationic intermediates. Just a decade after the the calcium-sensing receptor (CaR) was identified, pharmacological manipulation of the CaR is about to enter routine practice.

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Rheological disorders has been more prominent in patients with CS and an increase in blood plasma viscosity significantly exceeded the values noted in TIA/RIND group. One of the tumor lines expressed MAGE-A3, whereas none expressed HPV 16.

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Testing was performed at baseline in the afternoon, at 3 months in the afternoon, and at 6 months in the morning. These data suggest that in the nervous system of crustacean species a molecule with C-terminal homology to substance P and other tachykinins is released as a neuroregulator in the stomatogastric ganglion.

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A tumor arising in the pituitary fossa and having some of the histological and ultrastructural features of a recently described tumor, purportedly originating from the folliculo-stellate cells of the anterior pituitary, is presented. Then, a progressive decrease in the antigen-induced bronchoconstriction and mediator release was observed. Applicability of noncardioplegic coronary bypass to high-risk patients.

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In order to establish whether ketoconazole enhances or attenuates the immunosuppressive effect of prednisolone, the influence of ketoconazole on the kinetics of prednisolone and on the delayed hypersensitivity response was assessed in mice. Histology revealed decreased collateral thermal damage in FITC-enhanced welds.

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Adolescent depression: social network and family climate--a case-control study. As for organic anions, the renal clearance of some organic cations approaches the renal plasma flow.

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To evaluate the effect of nurse case management on the treatment of older women with breast cancer. In practice, however, the appropriate delivery of raw materials for the maintenance and repair of the body requires complex sensory and cognitive processes, such that flavour sensation arguably constitutes the pre-eminent example of an integrated multicomponent perceptual experience. We highlight the uncommon phenomenon of shared psychiatric disorder occurring in the context of OCD. Due to the poor quality concentration measurements at the surface of the clarifier, the model was not calibrated to perform well in concentration predictions at this surface. A report from that the presence of lactogenic immunity in pigs protected suckling piglets from porcine epidemic diarrhea virus (PEDV) infection suggested that inducing mucosal immune responses in lactating pigs is an effective way of protecting swine from PEDV infection.

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The vaccination method is used to induce antibody response against disease-related proteins by immunization with modified pathological antigen as preventive therapy to acquire disease resistance. A case of unexpected death due to right-sided infective endocarditis (IE) in a 44-year-old female methamphethamine abuser is presented.